Composition and antimalarial activity of the volatile oil of aerial part of halimodendron halodendron

  • Zh. Kozhamkulova Al–farabi Kazakh National University, School of Chemistry, Department of Organic and Natural Products Chemistry, Almaty
  • G. Zhusupova Al–farabi Kazakh National University, School of Chemistry, Department of Organic and Natural Products Chemistry, Almaty
  • Zh. Abilov Al–farabi Kazakh National University, School of Chemistry, Department of Organic and Natural Products Chemistry, Almaty
  • A. Gadetskaya Al–farabi Kazakh National University, School of Chemistry, Department of Organic and Natural Products Chemistry, Almaty
  • S. Ross National Center for Natural Products Research, School of Pharmacy, The University of Mississippi, University, MS 38677; Department of Pharmacognosy, School of Pharmacy, The University of Mississippi, University, MS 38677

Abstract

The chemical composition of essential oil obtained by steam distillation from the flower, leaf and stem of Halimodendron halodendron, which is endemic to Kazakhstan, were analysed by GC/FID and GC/MS. The oil has unpleasant smell indicating that the oil composition is different than regular volatile oils. The percentage of the volatile oil in the air–dried plant material is 0.013 % (w/w).The components of the oil were identified by comparing their retention time and mass fragmentation patterns with those of the available references and / or with published data as well as through GCMS library search. This is the first report of the composition of the volatile oil of Halimodendron halodendron. The Volatile oil showed antimalarial activity (Plasmodium falciparum – 50% inhibition).

References

1. Лесная энциклопедия: В 2–х т., т.2/Гл.ред. Воробьев Г.И.; Ред.кол.: Анучин Н.А., Атрохин В.Г., Виноградов В.Н. и др. – М.: Сов. энциклопедия, 1986.– C.631.
2. Adams , R.P., Identification of Essential oils by Ion Trap Mass Spectroscopy, Academic Press, New–York, 1989.
Published
2011-03-30
How to Cite
Kozhamkulova, Z., Zhusupova, G., Abilov, Z., Gadetskaya, A., & Ross, S. (2011). Composition and antimalarial activity of the volatile oil of aerial part of halimodendron halodendron. Chemical Bulletin of Kazakh National University, (1), 294-297. Retrieved from https://bulletin.chemistry.kz/index.php/kaznu/article/view/922
Section
Other Papers