Possibilities for decreasing detection limits of analytical methods for determination of transformation products of unsymmetrical dimethylhydrazine in environmental samples

Keywords: high-resolution mass spectrometry, tandem mass spectrometry, dynamic headspace extraction, analysis of trace concentration, unsymmetrical dimethylhydrazine, environment


Most rockets of middle and heavy class launched from Kazakhstan, Russia, China and other countries still use highly toxic unsymmetrical dimethylhydrazine (UDMH) as a liquid propellant. Study of migration, distribution and accumulation of UDMH transformation products in environment and human health impact assessment of space rocket activity are currently complicated due to the absence of analytical methods allowing detection of trace concentrations of these compounds in analyzed samples. This paper reviews methods and approaches, which can be applied for development of such methods. Detection limits at a part-per-trillion (ppt) level may be achieved using most selective and sensitive methods based on gas or liquid chromatography in combination of tandem or high-resolution mass spectrometry. In addition, 1000-fold concentration of samples or integrated sample preparation methods, e.g., dynamic headspace extraction, are required. Special attention during development and application of such methods must be paid to purity of laboratory air, reagents, glassware and analytical instruments.

Author Biographies

Bulat Kenessov, al-Farabi Kazakh National University, Almaty

Center of Physical Chemical Methods of Research and Analysis, Almaty

Center of Physical Chemical Methods of Research and Analysis, Vice-Director on International Relations

Nadezhda Bakaikina, al-Farabi Kazakh National University, Almaty

Center of Physical Chemical Methods of Research and Analysis, Almaty

Master student

Alma Ormanbekovna Bimaganbetova, Scientific-Research Center “Garysh-Ekologiya”, Almaty


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How to Cite
Kenessov, B., Bakaikina, N., & Bimaganbetova, A. (2015). Possibilities for decreasing detection limits of analytical methods for determination of transformation products of unsymmetrical dimethylhydrazine in environmental samples. Chemical Bulletin of Kazakh National University, (4), 50-58. https://doi.org/https://doi.org/10.15328/cb654
Analytical Chemistry