Chitosan based hydrogels and their use in medicine
Keywords:
hydrogels, сhitosan, drug delivery, wound dressings
Abstract
Chitosan is a natural biopolymer, polysaccharide, a product of chitin deacetylation. Chitosan is a non-toxic, biocompatible and biodegradable polymer with high biological activity and stability in the environment. In addition, chitosan is obtained from natural renewable resources and is an inexpensive substance. Due to all these properties, chitosan is widely used in practical medicine, for example, in the form of hydrogel dosage forms in combination with natural and synthetic polymers.
This review is focused on polymer hydrogel materials based on chitosan. Special attention is paid to the preparation and use of wound dressings for the treatment of wounds of various etiologies. The use of hydrogel wound dressings based on this polysaccharide allows to create a protective shell on the surface of various wounds, to prolong delivery of antibacterial agents, peptides and other active substances, which significantly increases the effectiveness of therapy. Bactericidal and sorption properties of chitosan-based hydrogels established in experimental and clinical studies are discussed.
References
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46 Croisier F, Jérôme C (2013) Eur Polym J 49(4):780–792. Crossref
47 Ahmed S (2014) Journal of Applicable Chemistry 3(2):493-503.
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52 Anisha BS, Biswas R, Chennazhi KP, Jayakumar R (2013) Int J Biol Macromol 62:310-320. Crossref
53 Sámano-Valencia C, Martinez-Castanon GA, Martínez-Martínez RE, Loyola-Rodríguez JP, Reyes-Macías JF, et al (2013) Mater Lett 106:413-416. Crossref
54 Sudheesh Kumar PT, Lakshmanan VK, Anilkumar TV, Ramya C, Reshmi P, et al (2012) ACS Appl Mater Inter 4(5):2618-2629. Crossref
55 Aziz MA, Cabral JD, Brooks HJL, Moratti SC, Hanton LR (2012) Antimicrob Agents Chemother 56(1):280-287. Crossref
56 Mochalova AE, Budruev AV, Oleinik AV, Smirnova LA (2009) Promising materials [Perspektivnyye materialy] 5:61-65. (In Russian)
57 Miguel SP, Ribeiro MP, Brancal H, Coutinho P, Correia IJ (2014) Carbohydr Polym 111:366-373. Crossref
58 Ahmed S, Ikram S (2016) Achiev Life Sci 10(1):27-37. Crossref
59 Arteche Pujana M, Pérez-Álvarez L, Cesteros Iturbe LC, Katime I (2013) Carbohydr Polym 94:836-842. Crossref
60 Berger J, Reist M, Mayer JM, Felt O, Peppas NA, Gurny R (2004) Eur J Pharm Biopharm 57(1):19-34. Crossref
61 Abbasipour M, Mirjalili M, Khajavi R, Majidi MM (2014) J Eng Fibers Fabr 9(1):124-130. Crossref
62 Wang L, Khor E, Wee A, Lim LY (2002) J Biomed Mater Res 63(5):610-618. Crossref
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64 Hao JY, Mi FL, Shyu SS, Wu YB, Schoung JY (2002) J Biomed Mater Res 59(3):438-449. Crossref
65 Ishihara M, Ono K, Sato M, Nakanishi K, Saito Y, et al (2001) Wound Repair and Regeneration 9(6):513-521. Crossref
66 Obara K, Ishihara M, Ishizuka T, Fujita M, Ozeki Y, Maehara T, Saito Y, Yura H, Matsui T, Hattori H, Kikuchi M, Kurita A (2003) Biomaterials 24(20):3437-3444. Crossref
67 Kamoun EA, Chen X, Mohy Eldin MS, Kenawy ERS (2015) Arabian J Chem 8(1):1-14. Crossref
68 El Salmawi KM (2007) J Macromol Sci Part A Pure Appl Chem 44:541-545. Crossref
69 Khorasani MT, Joorabloo A, Moghaddam A, Shamsi H, Mansoori Moghadam Z (2018) Int J Biol Macromol 114:1203-1215. Crossref
70 Chen SH, Tsao CT, Chang CH, Lai YT, Wu MF, et al (2013) Mater Sci Eng C 33:2584-2594. Crossref
71 Radhakumary C, Antonty M, Sreenivasan K (2011) Carbohydr Polym 83:705-713. Crossref
72 Mayorova AV, Sysuev BB, Khanalieva IA, Vikhrova IV (2018) Pharmacy & Pharmacology [Farmatsiya i farmakologiya] 1:4-32. (In Russian). Crossref
73 Prokopchuk NR, Melamed VD, Prishchepenko DV (2017) Proceedings of BSTU [Trudy BGTU]1:15-22. (In Russian)
74 Zhao R, Li X, Sun B, Zhang Y, Zhang D, et al (2014) Int J Biol Macromol 68:92-97. Crossref
2 Bhowmik D, Gopinath H, Kumar BP, Duraivel S, Kumar KPS (2012) Pharma Innovation 1(10):24-32.
3 Chanda J (1994) Biomaterials 15:465-465. Crossref
4 Oh JK, Lee DI, Park JM (2009) Prog Polym Sci 34:1261-1282. Crossref
5 Kumari A, Yadav SK, Yadav SC (2010) Colloids Surf B 75:1-18. Crossref
6 Peppas NA, Bures P, Leobandung W, Ichikawa H (2000) Eur J Pharm Biopharm 50:27-46. Crossref
7 Hoffman AS (2012) Adv Drug Delivery Rev 64:18-23. Crossref
8 Gao L, Gan H, Meng Z, Gu R, Wu Z, et al (2014) Colloids Surf B 117:398-405. Crossref
9 Wichterle O, Lím D (1960) Nature 185:117-118. Crossref
10 Lim F, Sun AM (1980) Science 210:908-910. Crossref
11 Caló E, Barros JMSD, Fernández-Gutiérrez M, San Román J, Ballamy L, Khutoryanskiy VV (2016) RSC Adv 6(60):55211-55219. Crossref
12 Boateng JS, Matthews KH, Stevens HNE (2008) J Pharm Sci 97:2892-2923. Crossref
13 Winter GD (1962) Nature 193:293-294. Crossref
14 Kamoun EA, Kenawy ERS, Chen X (2017) J Adv Res 8:217-233. Crossref
15 Huang S, Fu X (2010) J Control Release 142:149-159. Crossref
16 Seaman S (2002) J Am Podiatr Med Assoc 92(1):24-33. Crossref
17 Azad AK, Sermsintham N, Chandrkrachang S, Stevens WF (2004) J Biomed Mater Res B 69(2):216-222. Crossref
18 Grigoryeva MV (2011) Biotechnology [Biotekhnolohiya] 2:9-23. (In Russian)
19 Pawar HV, Tetteh J, Boateng JS (2013) Colloids Surf B 102:102-110. Crossref
20 Caccavo D, Cascone S, Lamberti G, Barba AA (2015) Mol Pharm 12(2):473-483. Crossref
21 Koehler J, Brandl FP, Goepferich AM (2018) Eur Polym J 100:1-11. Crossref
22 Jin SG, Yousaf AM, Kim KS, Kim DW, Kim DS, et al (2016) Int J Pharm 501(1-2):160-166. Crossref
23 Nolff MC, Albert R, Reese S, Meyer-Lindenberg A (2018) Vet Comp Orthop Traumatol 31(4):22-238. Crossref
24 Caló E, Khutoryanskiy VV (2015) Eur Polym J 65:252-267. Crossref
25 Vinnik YuS, Markelova NM, Tyuryumin VS (2013) Siberian Medical Review [Sibirskoye meditsinskoye obozreniye] 1:18-24. (In Russian)
26 Osikov MV, Simonyan EV, Grigoryeva GP, Saedgalina OT, Nozhkina NN (2014) Fundamental Research [Fundamental’nyye issledovaniya] 10:1632-1639.
27 Kumar A, Wang X, Nune KC, Misra RDK (2017) Int Wound J 14(6):1076-1087. Crossref
28 Vinnik YuS, Markelova NM, Solovyova NS, Shishatskaya EI, Kuznetsov MN, Zuev AP (2015) Surgery News [Novosti khirurgii] 5:552-558. (In Russian). Crossref
29 Legonkova OA, Alekseev AA (2015) Bulletin of Roszdravnadzor [Vestnik Roszdravnadzora] 6:66-68. (In Russian)
30 Blenov AV (2006) Surgery News [Novosti khirurgii] 14(1):9-19. (In Russian)
31 Anjum S, Arora A, Alam MS, Gupta B (2016) Int J Pharm 508(1-2):92-101. Crossref
32 Pinho E, Soares G (2018) J Mater Chem B 6(13):1887-1898. Crossref
33 Ou K, Wu X, Wang B, Meng C, Dong X, He J (2017) Cellulose 24(11):5211-5224. Crossref
34 Thakur VK, Thakur MK (2014) ACS Sustain Chem Eng 2(12):2637-2652. Crossref
35 Shablin DV, Pavlenko SG, Evglevsky AA, Bondarenko PP, Khuranov AA (2013) Fundamental Research [Fundamental’nyye issledovaniya] 12:361-365. (In Russian)
36 Kumar MNVR, Muzzarelli RAA, Muzzarelli C, Sashiwa H, Domb AJ (2004) Chem Rev 104(12):6017-6084. Crossref
37 Kean T, Thanou M (2010) Adv Drug Delivery Rev 62(1):3-11. Crossref
38 Deepachitra R, Pujitha Lakshmi R, Sivaranjani K, Helan Chandra J, Sastry TP (2015) J Chem Pharm Sci 8(2):324-329.
39 Dai T, Tanaka M, Huang YY, Hamblin MR (2011) Expert Rev Anti Infect Ther 9(7):857-879. Crossref
40 Durán-Lobato M, Martín-Banderas L, Gonçalves LMD, Fernández-Arévalo M, Almeida AJ (2015) J Nanopart Res 17(2):2875-2889. Crossref
41 Hamdine M, Heuzey MC, Bégin A (2006) Rheol Acta 45(5):659-675. Crossref
42 Paul W, Sharma CP (2004) Trends in Biometerials and Artificial Organs 18(1):18-23.
43 Raafat D, Von Bargen K, Haas A, Sahl HG (2008) Appl Environ Microbiol 74:3764-3773. Crossref
44 Goy RC, De Britto D, Assis OBG (2009) Polimeros 19(3):241-247. Crossref
45 Chung YC, Chen CY (2008) Bioresour Technol 99:2806-2814. Crossref
46 Croisier F, Jérôme C (2013) Eur Polym J 49(4):780–792. Crossref
47 Ahmed S (2014) Journal of Applicable Chemistry 3(2):493-503.
48 Mozalewska W, Czechowska-Biskup R, Olejnik AK, Wach RA, Ulański P (2017) Radiat Phys Chem 134:1-7. Crossref
49 Simões D, Miguel SP, Ribeiro MP, Coutinho P (2018) Eur J Pharm Biopharm 127:130-141. Crossref
50 Bukina YuA, Sergeeva EA (2012) Bulletin of the KTU [Vestnik KTU] 7:125-128. (In Russian)
51 Tyliszczak B, Drabczyk A, Kudłacik-Kramarczyk S, Bialik-Wąs K, Kijkowska R, Sobczak-Kupiec A (2017) Colloids Surf B 160:325-330. Crossref
52 Anisha BS, Biswas R, Chennazhi KP, Jayakumar R (2013) Int J Biol Macromol 62:310-320. Crossref
53 Sámano-Valencia C, Martinez-Castanon GA, Martínez-Martínez RE, Loyola-Rodríguez JP, Reyes-Macías JF, et al (2013) Mater Lett 106:413-416. Crossref
54 Sudheesh Kumar PT, Lakshmanan VK, Anilkumar TV, Ramya C, Reshmi P, et al (2012) ACS Appl Mater Inter 4(5):2618-2629. Crossref
55 Aziz MA, Cabral JD, Brooks HJL, Moratti SC, Hanton LR (2012) Antimicrob Agents Chemother 56(1):280-287. Crossref
56 Mochalova AE, Budruev AV, Oleinik AV, Smirnova LA (2009) Promising materials [Perspektivnyye materialy] 5:61-65. (In Russian)
57 Miguel SP, Ribeiro MP, Brancal H, Coutinho P, Correia IJ (2014) Carbohydr Polym 111:366-373. Crossref
58 Ahmed S, Ikram S (2016) Achiev Life Sci 10(1):27-37. Crossref
59 Arteche Pujana M, Pérez-Álvarez L, Cesteros Iturbe LC, Katime I (2013) Carbohydr Polym 94:836-842. Crossref
60 Berger J, Reist M, Mayer JM, Felt O, Peppas NA, Gurny R (2004) Eur J Pharm Biopharm 57(1):19-34. Crossref
61 Abbasipour M, Mirjalili M, Khajavi R, Majidi MM (2014) J Eng Fibers Fabr 9(1):124-130. Crossref
62 Wang L, Khor E, Wee A, Lim LY (2002) J Biomed Mater Res 63(5):610-618. Crossref
63 Mi FL, Shyu SS, Wu YB, Lee ST, Shyong JY, Huang RN (2001) Biomaterials 22(2):165–173. Crossref
64 Hao JY, Mi FL, Shyu SS, Wu YB, Schoung JY (2002) J Biomed Mater Res 59(3):438-449. Crossref
65 Ishihara M, Ono K, Sato M, Nakanishi K, Saito Y, et al (2001) Wound Repair and Regeneration 9(6):513-521. Crossref
66 Obara K, Ishihara M, Ishizuka T, Fujita M, Ozeki Y, Maehara T, Saito Y, Yura H, Matsui T, Hattori H, Kikuchi M, Kurita A (2003) Biomaterials 24(20):3437-3444. Crossref
67 Kamoun EA, Chen X, Mohy Eldin MS, Kenawy ERS (2015) Arabian J Chem 8(1):1-14. Crossref
68 El Salmawi KM (2007) J Macromol Sci Part A Pure Appl Chem 44:541-545. Crossref
69 Khorasani MT, Joorabloo A, Moghaddam A, Shamsi H, Mansoori Moghadam Z (2018) Int J Biol Macromol 114:1203-1215. Crossref
70 Chen SH, Tsao CT, Chang CH, Lai YT, Wu MF, et al (2013) Mater Sci Eng C 33:2584-2594. Crossref
71 Radhakumary C, Antonty M, Sreenivasan K (2011) Carbohydr Polym 83:705-713. Crossref
72 Mayorova AV, Sysuev BB, Khanalieva IA, Vikhrova IV (2018) Pharmacy & Pharmacology [Farmatsiya i farmakologiya] 1:4-32. (In Russian). Crossref
73 Prokopchuk NR, Melamed VD, Prishchepenko DV (2017) Proceedings of BSTU [Trudy BGTU]1:15-22. (In Russian)
74 Zhao R, Li X, Sun B, Zhang Y, Zhang D, et al (2014) Int J Biol Macromol 68:92-97. Crossref
Published
2020-05-04
How to Cite
АbilovaG., Makhayeva, D., Irmukhametova, G., & Khutoryanskiy, V. (2020). Chitosan based hydrogels and their use in medicine. Chemical Bulletin of Kazakh National University, 97(2), 16-28. https://doi.org/https://doi.org/10.15328/cb1100
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