Kinetics of release of methylene blue immobilized in calcium alginate microparticles
Abstract
The swelling kinetics of microparticles obtained with different concentrations of calcium chloride was studied to learn the ability of sodium alginate to gelation. To increase the effect of prolongation it is necessary to obtain microparticles with sustained release of drugs. For this purpose the drying kinetics of alginate microparticles was investigated. Also the kinetics of release of methylene blue immobilized in calcium alginate microparticles was studied. It was found that the release of methylene blue from the microparticles depends on the amount of immobilized material.
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