Possibilities for decreasing detection limits of analytical methods for determination of transformation products of unsymmetrical dimethylhydrazine in environmental samples
Abstract
Most rockets of middle and heavy class launched from Kazakhstan, Russia, China and other countries still use highly toxic unsymmetrical dimethylhydrazine (UDMH) as a liquid propellant. Study of migration, distribution and accumulation of UDMH transformation products in environment and human health impact assessment of space rocket activity are currently complicated due to the absence of analytical methods allowing detection of trace concentrations of these compounds in analyzed samples. This paper reviews methods and approaches, which can be applied for development of such methods. Detection limits at a part-per-trillion (ppt) level may be achieved using most selective and sensitive methods based on gas or liquid chromatography in combination of tandem or high-resolution mass spectrometry. In addition, 1000-fold concentration of samples or integrated sample preparation methods, e.g., dynamic headspace extraction, are required. Special attention during development and application of such methods must be paid to purity of laboratory air, reagents, glassware and analytical instruments.References
1 Carlsen L, Kenesova OA, Batyrbekova SE (2007) Chemosphere 67:1108-1116. http://dx.doi.org/10.1016/j.chemosphere.2006.11.046
2 Carlsen L, Kenessov BN, Batyrbekova SY, Kolumbaeva SZ, Shalakhmetova TM (2009) Environ Toxicol Pharmacol 28:448-52. http://dx.doi.org/10.1016/j.etap.2009.08.004
3 Kolumbayeva S, Begimbetova D, Shalakhmetova T, Saliev T, Lovinskaya A, Zhunusbekova B (2014) Ecotoxicology 23:1283-1291. http://dx.doi.org/10.1007/s10646-014-1271-1
4 Kenessov B, Alimzhanova M, Sailaukhanuly Y, Baimatova N, Abilev M, Batyrbekova S, et al. (2012) Sci Total Environ 427:78-85. http://dx.doi.org/10.1016/j.scitotenv.2012.04.017
5 Carlsen L, Kenessov BN, Batyrbekova SY (2009) Environ Toxicol Pharmacol 27:415-423. http://dx.doi.org/10.1016/j.etap.2009.01.005
6 Carlsen L, Kenessov BN, Batyrbekova SY (2008) Environ Health Insights 1:11-20.
7 Kenessov BN, Batyrbekova SY (2012) Chemical Bulletin of Kazakh National University 2:124-131. (In Russian). http://dx.doi.org/10.15328/chemb_2012_2124-131
8 Zhubatov Z, Kozlovskiy VA (2012) Report on the project “Evaluation of stability of natural ecosystems affected by space rocket activity. Experimental studies on justification of maximum allowable concentrations of toxic rocket fuel components and their transformation products.” Almaty, Kazakhstan.
9 Kosyakov DS, Ul’yanovskii N V, Pokryshkin SA, Lakhmanov DE, Shpigun OA (2015) Int J Environ Anal Chem 95:1321-1337. http://dx.doi.org/10.1080/03067319.2015.1090569
10 Hernández F, Sancho J V., Ibáñez M, Abad E, Portolés T, Mattioli L (2012) Anal Bioanal Chem 403:1251-1264. http://dx.doi.org/10.1007/s00216-012-5844-7
11 Black RM, Clarke RJ, Read RW, Reid MTJ (1994) J Chromatogr A 662:301-321. http://dx.doi.org/10.1016/0021-9673(94)80518-0
12 US EPA (2004) Method 521. Determination of nitrosamines in drinking water by solid phase extraction and capillary column and solid phase extraction and capillary column gas chromatography.
13 Kenessov B, Batyrbekova S, Nauryzbayev M, Bekbassov T, Alimzhanova M, Carlsen L (2008) Chromatographia 67:421-424. http://dx.doi.org/10.1365/s10337-008-0535-4
14 Llompart M, Li K, Fingas M (1999) Talanta 48:451-459. http://dx.doi.org/10.1016/S0039-9140(98)00263-X
15 Guo J, Jiang R, Pawliszyn J (2013) J Chromatogr A 1307:66-72. http://dx.doi.org/10.1016/j.chroma.2013.07.110
16 Zhang Z, Pawliszyn J (1993) Anal Chem 65:1843-1852. http://dx.doi.org/10.1021/ac00062a008
17 Zhang Z, Pawliszyn J (1995) Anal Chem 67:34-43. http://dx.doi.org/10.1021/ac00097a007
18 Ghiasvand AR, Hajipour S, Heidari N (2016) TrAC Trends Anal Chem 77:54-65. http://dx.doi.org/10.1016/j.trac.2015.12.008
19 Kenessov BN, Koziel JA, Grotenhuis T, Carlsen L (2010) Anal Chim Acta 674:32-39. http://dx.doi.org/10.1016/j.aca.2010.05.040
20 Yegemova S, Bakaikina N, Kenessov B, Koziel J, Nauryzbayev M (2015) Talanta 143:226-233. http://dx.doi.org/10.1016/j.talanta.2015.05.045
21 Bakaikina N, Kenessov B, Yegemova S, Koziel J (2015) Fast quantification of transformation products of rocket fuel unsymmetrical dimethylhydrazine in soil using solid-phase microextraction and GC-MS. Abstract of “Pacifichem-2015” Symposium, Honolulu, USA. ANYL 664.
22 Larreta J, Bilbao U, Vallejo A, Usobiaga A, Arana G, Zuloaga O (2008) Chromatographia 67:93-99. http://dx.doi.org/10.1365/s10337-007-0441-1
23 Buszewski B, Ligor T, Ulanowska A (2016) Determination of volatile organic compounds: Enrichment and analysis. Handbook of Trace Analysis. Springer International Publishing, Cham, Switzerland, 2016. P.403-430. http://dx.doi.org/10.1007/978-3-319-19614-5_14
24 Askari MDF, Maskarinec MP, Smith SM, Beam PM, Travis CC (1996) Anal Chem 68:3431-3433. http://dx.doi.org/10.1021/ac960009c
25 Kolb B, Ettre LS (2006) Static Headspace-Gas Chromatography: Theory and practice. John Wiley & Sons, Inc., Hoboken, NJ, USA. http://dx.doi.org/10.1002/0471914584
26 Kosyakov DS, Ul’yanovskii NV, Bogolitsyn KG, Shpigun OA (2014) Int J Environ Anal Chem 94:1254-1263. http://dx.doi.org/10.1080/03067319.2014.940342
27 Smolenkov AD, Rodin IA, Smirnov RS, Tataurova OG, Shpigun OA (2012) Moscow Univ Chem Bull 67:229-235. http://dx.doi.org/10.3103/S0027131412050057
28 Chen L, Wang H, Zeng Q, Xu Y, Sun L, Xu H, et al. (2009) J Chromatogr Sci 47:614-623. http://dx.doi.org/10.1093/chromsci/47.8.614
29 Choi K-J, Kim S-G, Kim C, Kim S-H (2007) Chemosphere 66:977-984. http://dx.doi.org/10.1016/j.chemosphere.2006.07.037
30 Barco-Bonilla N, Plaza-Bolaños P, Fernández-Moreno JL, Romero-González R, Frenich AG, Vidal JLM (2011) Anal Bioanal Chem 400:3537-3546. http://dx.doi.org/10.1007/s00216-011-5014-3
31 Nogueira JMF (2012) Anal Chim Acta 757:1-10. http://dx.doi.org/10.1016/j.aca.2012.10.033
32 Vrana B, Komancová L, Sobotka J (2016) Talanta 152:90–97. http://dx.doi.org/10.1016/j.talanta.2016.01.040
33 Herrington JS (2015) Ambient air sampling with whole-air, in-field concentration and Particulate Matter (PM) Methodologies (Chapter 4 in Monitoring of Air Pollutants: Sampling, Sample Preparation and Analytical Techniques). Elsevier, Oxford, UK, 2015. P.109-153. http://dx.doi.org/10.1016/bs.coac.2015.09.004
34 Herrington JS (2013) Anal Chem 85:7882-7888. http://dx.doi.org/10.1021/ac401522p
35 U.S. EPA (1999) Method TO-15. Determination of volatile organic compounds (VOCs) in air collected in specially-prepared canisters and analyzed by gas chromatography/ mass spectrometry (GC/MS).
36 Kim K-H, Kim Y-H, Brown RJC (2013) Anal Bioanal Chem 405:8397-8408. http://dx.doi.org/10.1007/s00216-013-7263-9
37 U.S. EPA (1999) Method TO-17: Compendium of methods for the determination of toxic organic compounds in ambient air, second Edition. Compendium method TO-17 Determination of volatile organic compounds in ambient air using active sampling onto sorbent tubes.
38 U.S. EPA (1986) Method TO-7. Method for the determination of n-nitrosodimethylamine in ambient air using gas chromatrography.
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